The Mini IVF Cycle: Worth A Try

It’s been a year since the mini IVF program was first offered at IVFMD and looking back at the data, we have reasons to be positive! We found that about 85% of patients who went through the mini IVF cycle were able to receive at least one embryo created from their own eggs. These were patients who could not undergo regular IVF due to very low ovarian reserve, those whose remaining options were either donor egg IVF or adoption.

The mini IVF program has enabled patients with very few remaining eggs to conceive. We had patients who conceived with AMH as low as 0.1 ng/ml, and patients who found success with mini IVF after failing several rounds of aggressive IVF treatment.

In our experience, patients who benefited most from mini IVF were those with very low egg reserve (fewer than 5 antral follicles and/or AMH of 0.5 ng/ml or lower). The typical aggressive IVF stimulation protocol for them would require huge spending on medications of about $500 a day for 12-14 days. By combining natural FSH from the pituitary with a modest amount of medications, the mini IVF protocol provides just enough stimulation to allow the follicles to grow while reducing medication cost.

Some might argue that maximum stimulation could have resulted in collection of more eggs for some patients. In our opinion, however, the huge increase in the cost does not justify the potential gain of just a few more eggs. The difference in medication costs can be substantial- $1,000 for mini IVF vs. $6,000-8,000 for an aggressive IVF protocol.

Our Mini IVF program is consisted of a Stimulation cycle and a Frozen Embryo Transfer cycle. The saving on medications can be used to afford a second round of Stimulation cycle to accumulate embryos. Due to prolonged use of clomiphene during the Stimulation cycle, which can make the endometrium unfavorable for implantation, the resulting embryos are frozen for future transfer.

Even when the mini IVF cycle doesn’t result in pregnancy, for many women having a chance to receive their own embryos is priceless and can help them with closure to move to the next stage in their journey toward parenthood. In this regard, the mini IVF cycle is worth a try.

Author
Sy Le, M.D. Dr. Le is the founder of IVFMD and has aspired from day one to make leading edge fertility treatment as affordable as possible. He has special interest in all aspects of Assisted Reproductive Technologies, especially IVF protocols for women with low ovarian reserve.

You Might Also Enjoy...

Recurrent Pregnancy Loss: You're Not Alone

Miscarriages happen to 80% of women in the first trimester. But if it’s your second or third loss, you need more than stats, you need answers. Here’s what you should know about repeated miscarriages.

5 Telltale Signs of Endometriosis

From the muscle fibers in your heart to the hard nails that protect your fingertips, every human tissue has a specific role. But if you have endometriosis, your uterine tissue has gone rogue. Learn how to spot the signs of this problematic condition.

How Ovulation Induction Works

When irregular ovulation stands between you and the family you’re planning, the solution may be ovulation induction. Here’s how it works and how to find out if you might be a good candidate.

I Regret Having My Tubes Tied

Everyone has made a decision they later regret, from tattoos to hairstyles. Fortunately, many can be reversed. If you had your tubes tied and wish you hadn’t, you may be able to restore your fertility with tubal reversal.

What's Involved in a Semen Analysis?

Was your vasectomy — or vasectomy reversal — successful? Need to find out whether your sperm are healthy and viable? A simple semen analysis can give you all the answers you need. Here’s what to expect.